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What is the role of BDNF in synaptic plasticity?

BDNF-induced local protein synthesis and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a role in the formation of certain forms of memory. The effects of BDNF in LTP are mediated by TrkB ...

Is there a link between BDNF and excitotoxicity?

Brain-derived neurotrophic factor (BDNF) Researchers have recently discovered a link between BDNF, mutant huntingtin, and excitotoxicity, a process by which brain cells die after stimulation. The mutant huntingtin protein invariably leads to the death of nerve cells in the striatum, the region of the brain needed for movements; however,...

What is the role of BDNF in LTP?

Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a role in the formation of certain forms of memory. The effects of BDNF in LTP are mediated by TrkB (tropomyosin-related …

What is the function of BDNF in the hippocampus?

Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a role in the formation of certain forms of memory.

Last Update: Oct 2021


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